Yutaka Koyama Selected Research

FR 139317

1/2018	Delayed Administration of BQ788, an ETB Antagonist, after Experimental Traumatic Brain Injury Promotes Recovery of Blood-Brain Barrier Function and a Reduction of Cerebral Edema in Mice.
1/2014	Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice.

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Yutaka Koyama Research Topics

Disease

7	Brain Edema (Cerebral Edema) 01/2020 - 04/2004
6	Pain (Aches) 01/2017 - 01/2012
5	Frailty 06/2022 - 05/2017
4	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2021 - 01/2018
4	Aortic Valve Stenosis (Aortic Stenosis) 01/2018 - 04/2015
3	Neointima 04/2022 - 12/2019
3	Brain Diseases (Brain Disorder) 04/2021 - 04/2013
3	Hypoalbuminemia 01/2021 - 03/2017
3	Thrombosis (Thrombus) 01/2021 - 11/2007
3	Diabetes Mellitus 10/2020 - 02/2016
3	Hyperalgesia 01/2017 - 01/2013
3	Coronary Artery Disease (Coronary Atherosclerosis) 05/2016 - 12/2015
3	Edema (Dropsy) 04/2015 - 03/2005
3	Hypertrophy 12/2014 - 03/2002
2	ST Elevation Myocardial Infarction 03/2022 - 01/2022
2	Brain Injuries (Brain Injury) 04/2021 - 08/2003
2	Stroke (Strokes) 01/2021 - 08/2013
2	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 10/2020
2	Gliosis 01/2019 - 12/2014
2	Chronic Pain 01/2017 - 01/2013
2	Type 2 Diabetes Mellitus (MODY) 05/2016 - 01/2016
2	Cold Injury 09/2015 - 01/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2015 - 08/2013
2	Brain Ischemia (Cerebral Ischemia) 12/2012 - 04/2004
1	Atherosclerosis 04/2022
1	Lymphoma (Lymphomas) 02/2022
1	Cardiogenic Shock 01/2022
1	Atrioventricular Block 04/2021
1	Myocardial Infarction 01/2021
1	Hemorrhage 01/2021
1	Peripheral Arterial Disease 01/2021
1	Unstable Angina 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Chronic Renal Insufficiency 10/2020
1	Hypertension (High Blood Pressure) 10/2020
1	Heart Failure 10/2020
1	Ischemia 01/2020
1	Aortic Dissection 01/2020
1	Parkinson Disease (Parkinson's Disease) 01/2020
1	Rupture 01/2020
1	Aneurysm (Aneurysms) 11/2019
1	Aortic Aneurysm (Aneurysm, Aortic) 11/2019
1	Mitral Valve Insufficiency (Mitral Regurgitation) 10/2019
1	Diverticulum 10/2018
1	Nervous System Diseases (Neurological Disorders) 01/2018

Drug/Important Bio-Agent (IBA)

5	Pharmaceutical PreparationsIBA 02/2022 - 07/2004
5	Endothelins (Endothelin)IBA 04/2021 - 08/2003
5	AlbuminsIBA 01/2021 - 04/2004
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 01/2012
4	Endothelin-1 (Endothelin 1)IBA 04/2021 - 01/2018
4	Serum AlbuminIBA 01/2021 - 03/2017
4	BQ 788IBA 01/2020 - 01/2014
3	Biomarkers (Surrogate Marker)IBA 06/2022 - 09/2017
3	Matrix Metalloproteinases (MMPs)IBA 09/2015 - 01/2012
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2015 - 01/2012
3	Nerve Growth Factors (Neurotrophins)IBA 08/2013 - 08/2003
3	GW9508IBA 01/2013 - 01/2012
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 12/2014
2	FR 139317IBA 01/2018 - 01/2014
2	Evans Blue (Blue, Evans)FDA Link 01/2018 - 01/2014
2	Nonesterified Fatty Acids (NEFA)IBA 01/2017 - 01/2016
2	Dipeptidyl-Peptidase IV InhibitorsIBA 05/2016 - 01/2016
2	Sitagliptin Phosphate (Januvia)FDA Link 05/2016 - 01/2016
2	IRL 2500IBA 09/2015 - 01/2014
2	Formaldehyde (Formol)FDA Link 01/2013 - 01/2012
2	SEA 0400IBA 03/2005 - 04/2004
1	oxidized low density lipoproteinIBA 04/2022
1	Everolimus FDA Link 04/2022
1	LDL Lipoproteins (beta Lipoproteins)IBA 04/2022
1	Immunoglobulin A (IgA)IBA 02/2022
1	CreatinineIBA 01/2021
1	FibrinIBA 01/2021
1	omega-Chloroacetophenone (Mace)IBA 01/2021
1	Contrast MediaIBA 10/2020
1	ambrisentan FDA Link 01/2020
1	Bosentan (Tracleer)FDA Link 01/2020
1	Angiopoietin-1IBA 01/2020
1	Heme Oxygenase-1IBA 01/2020
1	Endothelin Receptor AntagonistsIBA 01/2020
1	2',4'-dichlorobenzamil amiloride (DCBA)IBA 12/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2019
1	Peptides (Polypeptides)IBA 01/2019
1	Vasoconstrictor AgentsIBA 01/2019
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2019
1	SodiumIBA 01/2018

Therapy/Procedure

12	Transcatheter Aortic Valve Replacement 04/2021 - 04/2015
5	Stents 04/2022 - 11/2007
4	Percutaneous Coronary Intervention 03/2022 - 01/2016
4	Therapeutics 01/2021 - 01/2017
2	Catheters 10/2020 - 09/2017
2	Endovascular Aneurysm Repair 01/2020 - 11/2019
1	Extracorporeal Membrane Oxygenation 01/2022
1	Patient Readmission 01/2021
1	Renal Dialysis (Hemodialysis) 10/2020
1	Aftercare (After-Treatment) 12/2019
1	Surgical Instruments (Clip) 10/2019
1	Sternotomy 10/2018
1	Thoracotomy 10/2018
1	Intravenous Administration 01/2018